Inform your physician before starting this treatment if you have liver diseases. Inform your physician before starting this treatment if you are pregnant or think you might be pregnant.Ĭonsult your physician for advice before taking this medicine if you are breastfeeding your child. Your physician will decide the timing and dose of this medicine depending on your condition. Your physician will inject this medicine into your vein. Zehnder, Drugs Used in Disorders of Coagulation, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 608-625.

Reversal of the anticoagulant effect of Dabigatran: idarucizumab, National Institute for Health and Care Excellence (NICE),,.Boehringer Ingelheim Pharmaceuticals, Inc., US Food & Drug Administration,,.Boehringer Ingelheim International GmbH, Electronic Medicines Compendium (EMC),,.Keep the product in the outer carton to protect it from light.

Inform your doctor about any medications you are taking or have taken before the treatment. It binds to Dabigatran and its metabolites and blocks its anticoagulant activity. Its action is specific to Dabigatran and not much effective against other anticoagulants. Idarucizumab is a human monoclonal antibody that has a very high affinity to Dabigatran.

Life-threatening or uncontrolled bleeding.

The reversal of anticoagulant effects is needed in the following conditions: Your physician might administer you a second dose of Praxbind 2.5gm Injection if bleeding reoccurs. The most frequently occurring side effect associated with anticoagulant use is bleeding, ranging from mild to severe complications. Your physician will prescribe this medicine when there is an emergency need to inactivate the anticoagulant effect of Dabigatran. It is indicated to reverse the anticoagulant effect of medicine called Dabigatran. Praxbind 2.5gm Injection consists of the active substance Idarucizumab.